Estudio piloto para determinar la asociación entre la microbiota intestinal y la fractura de cadera por fragilidad / Pilot study to determine the association between gut microbiota and fragility hip fracture

Introducción: Las fracturas de cadera son la causa más frecuente de ingreso hospitalario en los servicios de ortopedia de Europa y suponen un importante problema sanitario. Por ello, es de gran interés identificar factores de riesgo adicionales que nos ayuden a comprender mejor la fisiopatología de estas fracturas y a mejorar nuestra capacidad preventiva. Existen datos suficientes para apoyar la teoría de la modulación de la masa ósea por la microbiota intestinal (osteomicrobiología); sin embargo, faltan estudios clínicos en humanos que relacionen directamente la microbiota con el riesgo de fractura de cadera. Material y métodos: Estudio observacional, analítico, de casos y controles. La muestra consta de 50 pacientes y se distribuye de la siguiente manera: 25 pacientes ancianos con fractura de cadera por fragilidad y 25 controles sanos sin fractura. Se analizó la microbiota intestinal mediante extracción de ADN de muestras de heces y secuenciación del ADN ribosómico 16S tras la generación de bibliotecas de genes. Resultados: La diversidad alfa reveló una elevación de los estimadores para el nivel taxonómico de clase en el grupo de fracturas de cadera. Los órdenes Bacteroidales, Oscillospirales, Lachnospirales, Peptostreptococcales-Tissierellales y Enterobacterales fueron los órdenes dominantes en ambos grupos. En los pacientes con fractura, se observó un aumento porcentual significativo del orden de Bacteroidales (p<0,001) y Peptostreptococcales-Tissierellales (p<0,005), así como una disminución de las del orden Lachnospirales (p<0,001) respecto a los controles. Conclusiones:Este estudio ha encontrado una asociación entre una microbiota específica en pacientes ancianos con fractura de cadera por fragilidad. Estos hallazgos abren la puerta a nuevas estrategias para prevenir las fracturas de cadera. Es posible que la modificación de la microbiota mediante probióticos se revele como un método eficaz para reducir el riesgo de fractura de cadera.(AU)

Introduction: Hip fractures are the most common cause of hospital admission to orthopaedic departments in Europe and they generate a major health problem. Therefore, it is of great interest to identify additional risk factors that will help us to better understand the pathophysiology of these fractures and improve our preventive capacity. There is sufficient data to support the theory of modulation of bone mass by gut microbiota (osteomicrobiology); however, there is a lack of human clinical studies directly linking microbiota to hip fracture risk. Material and methods: Observational, analytical, case–control study. The sample consisted of 50 patients and it was distributed as follows: 25 elderly patients with fragility hip fracture and 25 subjects without fracture. The intestinal microbiota was determined by DNA extraction from stool samples and 16S ribosomal DNA sequencing after generation of gene libraries. Results: Alpha diversity revealed an elevation of the estimators for the taxonomic class level in the hip fracture group. The orders Bacteroidales, Oscillospirales, Lachnospirales, Peptostreptococcales-Tissierellales and Enterobacterales were the dominant orders in both groups. In patients with fracture, a significant percentage increase in the orders Bacteroidales (p<.001) and Peptostreptococcales-Tissierellales (p<.005) was observed, as well as a decrease in the orders Lachnospirales (p<.001) compared to controls. Conclusions: This study has found an association between a specific microbiota in elderly patients with fragility hip fracture. These findings open the door to new strategies to prevent hip fractures. Modification of the microbiota through probiotics may prove to be an effective method to reduce the risk of hip fracture.(AU)

[Translated article] Pilot study to determine the association between gut microbiota and fragility hip fracture.

INTRODUCTION: Hip fractures are the most common cause of hospital admission to orthopaedic departments in Europe and they generate a major health problem. Therefore, it is of great interest to identify additional risk factors that will help us to better understand the pathophysiology of these fractures and improve our preventive capacity. There is sufficient data to support the theory of modulation of bone mass by gut microbiota (osteomicrobiology); however, there is a lack of human clinical studies directly linking microbiota to hip fracture risk. MATERIAL AND METHODS: Observational, analytical, case-control study. The sample consisted of 50 patients and it was distributed as follows: 25 elderly patients with fragility hip fracture and 25 subjects without fracture. The intestinal microbiota was determined by DNA extraction from stool samples and 16S ribosomal DNA sequencing after generation of gene libraries. RESULTS: Alpha diversity revealed an elevation of the estimators for the taxonomic class level in the hip fracture group. The orders Bacteroidales, Oscillospirales, Lachnospirales, Peptostreptococcales-Tissierellales and Enterobacterales were the dominant orders in both groups. In patients with fracture, a significant percentage increase in the orders Bacteroidales (p<.001) and Peptostreptococcales-Tissierellales (p<.005) was observed, as well as a decrease in the orders Lachnospirales (p<.001) compared to controls. CONCLUSIONS: This study has found an association between a specific microbiota in elderly patients with fragility hip fracture. These findings open the door to new strategies to prevent hip fractures. Modification of the microbiota through probiotics may prove to be an effective method to reduce the risk of hip fracture.

Pilot study to determine the association between gut microbiota and fragility hip fracture. / Estudio piloto para determinar la asociación entre la microbiota intestinal y la fractura de cadera por fragilidad.

INTRODUCTION: Hip fractures are the most common cause of hospital admission to orthopaedic departments in Europe and they generate a major health problem. Therefore, it is of great interest to identify additional risk factors that will help us to better understand the pathophysiology of these fractures and improve our preventive capacity. There is sufficient data to support the theory of modulation of bone mass by gut microbiota (osteomicrobiology); however, there is a lack of human clinical studies directly linking microbiota to hip fracture risk. MATERIAL AND METHODS: Observational, analytical, case-control study. The sample consisted of 50 patients and it was distributed as follows: 25 elderly patients with fragility hip fracture and 25 subjects without fracture. The intestinal microbiota was determined by DNA extraction from stool samples and 16S ribosomal DNA sequencing after generation of gene libraries. RESULTS: Alpha diversity revealed an elevation of the estimators for the taxonomic class level in the hip fracture group. The orders Bacteroidales, Oscillospirales, Lachnospirales, Peptostreptococcales-Tissierellales and Enterobacterales were the dominant orders in both groups. In patients with fracture, a significant percentage increase in the orders Bacteroidales (p<.001) and Peptostreptococcales-Tissierellales (p<.005) was observed, as well as a decrease in the orders Lachnospirales (p<.001) compared to controls. CONCLUSIONS: This study has found an association between a specific microbiota in elderly patients with fragility hip fracture. These findings open the door to new strategies to prevent hip fractures. Modification of the microbiota through probiotics may prove to be an effective method to reduce the risk of hip fracture.

Un método 3D para estimar el efecto de osteotomías desrotadoras sobre alteraciones torsionales de fémur / A 3D method to estimate the effect of derotational osteotomies over femoral maltorsion

Introducción y objetivos: La medición precisa de la torsión femoral es esencial para el diagnóstico, indicación y planificación preoperatoria de las osteotomías desrotadoras femorales en pacientes con inestabilidad patelofemoral o dolor anterior de rodilla. Se han descrito múltiples métodos de medición, con valores muy diferentes entre ellos y ninguno de ellos permite establecer la magnitud de la osteotomía necesaria para devolver la torsión a valores normales. El objetivo del presente trabajo es desarrollar un método de medición que permita no solo el diagnóstico de pacientes con alteraciones torsionales, sino también establecer la magnitud de la osteotomía necesaria durante la cirugía. Material y métodos: Se seleccionaron 30 pacientes sin antecedentes de patología patelofemoral que disponían de una tomografía completa de miembros inferiores por otros motivos, siendo considerados así pacientes normales. Se calculó su torsión femoral mediante los métodos de Jeanmart y de Murphy por dos radiólogos independientes. Por otra parte, dos cirujanos ortopédicos independientes realizaron la medición de la torsión mediante el método 3D propuesto. Se evaluó el comportamiento normal de los datos y se definió la variabilidad intra- e interobservador del método 3D mediante su coeficiente de correlación intraclase y mediante el gráfico de Bland-Altman, realizando una comparación cuantitativa y cualitativa respectivamente con los métodos clásicos. Se estableció el intervalo de confianza de los valores normales con el nuevo método 3D y finalmente, se analizó al patrón de regresión lineal entre los métodos de Jeanmart y Murphy con el método de medición 3D. Resultados: La media de torsión femoral con el método 3D fue de 12,74° (DE 5,96°, IC 95%: 11,67 a 13,82°). Con el método de Jeanmart, esta fue de 12,84° (DE 8,60°, IC 95%: 11,28 a 14,39°) y de 15,87° (DE 10,68°, IC 95%: 13,94 a 17,80°) con el método de Murphy.(AU)

Introduction and objectives: Accurate measurement of femoral torsion is essential to diagnosing, correct surgical decision-making, and the preoperative planning of derotational osteotomies in a subgroup of anterior knee pain patients and patellofemoral instability. Several measurement techniques have been described with great variability in the magnitude of the values. Moreover, none of them can predict the effect of rotational osteotomy on the femoral version value. The purpose of the present work is to develop a method to reliably measure femoral torsion as well as to evaluate the effects of osteotomy on the femoral version angle. Material and methods: 30 patients without previous signs neither symptoms of patellofemoral pain or patellofemoral instability and with a lower limbs CT were selected. Their femoral torsion was measured using the classic Jeanmart and the Murphy's method by two independent radiologists. Independently, two orthopedic surgeons measured femoral torsion with the 3D method described in this study. The intraclass coefficient correlation and the Bland–Altman tests were used to analyze qualitatively and quantitatively the intraobserver and interobserver variability of the method regarding the Jeanmart's and Murphy's method. The confidence interval of the Normal values of the new method were defined and a lineal regression analysis between the 3D-Jeanmart's and 3D-Muphy's methods was performed. Results: The mean femoral version with the 3D method was 12.74° (SD 5.96°, 95% CI: 11.67° to 13.82°). With Jeanmart's method, it was 12.84° (SD 8.60°, 95% CI: 11.28° to 14.39°) and 15.87° (SD 10.68°, 95% CI: 13.94° to 17.80°) with Murphy's method, being these differences not statistically significant. Both interobserver and intraobserver agreement of the 3D method were high.(AU)

[Translated article] A 3D method to estimate the effect of derotational osteotomies over femoral maltorsion / Un método 3D para estimar el efecto de osteotomías desrotadoras sobre alteraciones torsionales de fémur

Introducción y objetivos: La medición precisa de la torsión femoral es esencial para el diagnóstico, indicación y planificación preoperatoria de las osteotomías desrotadoras femorales en pacientes con inestabilidad patelofemoral o dolor anterior de rodilla. Se han descrito múltiples métodos de medición, con valores muy diferentes entre ellos y ninguno de ellos permite establecer la magnitud de la osteotomía necesaria para devolver la torsión a valores normales. El objetivo del presente trabajo es desarrollar un método de medición que permita no solo el diagnóstico de pacientes con alteraciones torsionales, sino también establecer la magnitud de la osteotomía necesaria durante la cirugía. Material y métodos: Se seleccionaron 30 pacientes sin antecedentes de patología patelofemoral que disponían de una tomografía completa de miembros inferiores por otros motivos, siendo considerados así pacientes normales. Se calculó su torsión femoral mediante los métodos de Jeanmart y de Murphy por dos radiólogos independientes. Por otra parte, dos cirujanos ortopédicos independientes realizaron la medición de la torsión mediante el método 3D propuesto. Se evaluó el comportamiento normal de los datos y se definió la variabilidad intra- e interobservador del método 3D mediante su coeficiente de correlación intraclase y mediante el gráfico de Bland-Altman, realizando una comparación cuantitativa y cualitativa respectivamente con los métodos clásicos. Se estableció el intervalo de confianza de los valores normales con el nuevo método 3D y finalmente, se analizó al patrón de regresión lineal entre los métodos de Jeanmart y Murphy con el método de medición 3D. Resultados: La media de torsión femoral con el método 3D fue de 12,74° (DE 5,96°, IC 95%: 11,67 a 13,82°). Con el método de Jeanmart, esta fue de 12,84° (DE 8,60°, IC 95%: 11,28 a 14,39°) y de 15,87° (DE 10,68°, IC 95%: 13,94 a 17,80°) con el método de Murphy.(AU)

Introduction and objectives: Accurate measurement of femoral torsion is essential to diagnosing, correct surgical decision-making, and the preoperative planning of derotational osteotomies in a subgroup of anterior knee pain patients and patellofemoral instability. Several measurement techniques have been described with great variability in the magnitude of the values. Moreover, none of them can predict the effect of rotational osteotomy on the femoral version value. The purpose of the present work is to develop a method to reliably measure femoral torsion as well as to evaluate the effects of osteotomy on the femoral version angle. Material and methods: 30 patients without previous signs neither symptoms of patellofemoral pain or patellofemoral instability and with a lower limbs CT were selected. Their femoral torsion was measured using the classic Jeanmart and the Murphy's method by two independent radiologists. Independently, two orthopedic surgeons measured femoral torsion with the 3D method described in this study. The intraclass coefficient correlation and the Bland–Altman tests were used to analyze qualitatively and quantitatively the intraobserver and interobserver variability of the method regarding the Jeanmart's and Murphy's method. The confidence interval of the Normal values of the new method were defined and a lineal regression analysis between the 3D-Jeanmart's and 3D-Muphy's methods was performed. Results: The mean femoral version with the 3D method was 12.74° (SD 5.96°, 95% CI: 11.67° to 13.82°). With Jeanmart's method, it was 12.84° (SD 8.60°, 95% CI: 11.28° to 14.39°) and 15.87° (SD 10.68°, 95% CI: 13.94° to 17.80°) with Murphy's method, being these differences not statistically significant. Both interobserver and intraobserver agreement of the 3D method were high.(AU)

[Translated article] A 3D method to estimate the effect of derotational osteotomies over femoral maltorsion.

INTRODUCTION AND OBJECTIVES: Accurate measurement of femoral torsion is essential to diagnosing, correct surgical decision-making, and the preoperative planning of derotational osteotomies in a subgroup of anterior knee pain patients and patellofemoral instability. Several measurement techniques have been described with great variability in the magnitude of the values. Moreover, none of them can predict the effect of rotational osteotomy on the femoral version value. The purpose of the present work is to develop a method to reliably measure femoral torsion as well as to evaluate the effects of osteotomy on the femoral version angle. MATERIAL AND METHODS: 30 patients without previous signs neither symptoms of patellofemoral pain or patellofemoral instability and with a lower limbs CT were selected. Their femoral torsion was measured using the classic Jeanmart and the Murphy's method by two independent radiologists. Independently, two orthopedic surgeons measured femoral torsion with the 3D method described in this study. The intraclass coefficient correlation and the Bland-Altman tests were used to analyze qualitatively and quantitatively the intraobserver and interobserver variability of the method regarding the Jeanmart's and Murphy's method. The confidence interval of the Normal values of the new method were defined and a lineal regression analysis between the 3D-Jeanmart's and 3D-Muphy's methods was performed. RESULTS: The mean femoral version with the 3D method was 12.74° (SD 5.96°, 95% CI: 11.67°-13.82°). With Jeanmart's method, it was 12.84° (SD 8.60°, 95% CI: 11.28°-14.39°) and 15.87° (SD 10.68°, 95% CI: 13.94°-17.80°) with Murphy's method, being these differences not statistically significant. Both interobserver and intraobserver agreement of the 3D method were high. CONCLUSION: The method presented in this study allows for the reliable quantification of femoral torsion in a reproducible way. This method can be applied in several open access 3D image programmes what makes its implementation in the healthcare centres possible from now on.

Aptitudes y conocimientos en medicina musculoesquelética en licenciados en medicina previos a su incorporación al sistema de residencia del Sistema Nacional de Salud / Skills and knowledge in musculoskeletal medicine in medical graduates prior to their incorporation into the residency system of the National Health System

Introducción: La enfermedad del sistema musculoesquelético es una causa frecuente de demanda asistencial. El conocimiento en medicina musculoesquelética (MME) debe ser esencial para gran parte de las especialidades. Desafortunadamente, gran parte de los médicos internos residentes (MIR) reconocen tener falta de confianza y de competencia en este campo. Material y métodos: Cincuenta MIR recién incorporados a su plaza (32 de ellos residentes de COT de la Comunidad Valenciana) completaron el test de competencia básica en MME de Freedman y Berstein. Además, realizaron un cuestionario sobre el grado de confianza a la hora de desempeñar 5 tareas habituales en la práctica clínica y sobre la percepción de la carga curricular de MME en su formación académica. Resultados: La puntuación media global obtenida en el test fue de 69,44% (SD 13,32%), mientras que la puntuación concreta para 5 preguntas que se consideraban «banderas rojas» fue de 14,34%(SD 2,58%). Ambas mostraron diferencias significativas entre los residentes de COT y otras especialidades.La mediana obtenida en la valoración del nivel de confianza en la exploración de heridas fue de 2 sobre 5 (IQR 2), con diferencias significativas (p=0,014) entre el grupo COT y el de otras especialidades. La percepción del tiempo dedicado en la facultad en materia de MME fue considerada como adecuada (mediana 3, IQR 1). El 64% modificaría el planteamiento de la parte práctica del currículo en MME. Conclusiones: La prueba global fue superada por el 50% de los residentes, lo cual pone de manifiesto que la enseñanza en MME es deficitaria durante el periodo universitario y formativo preMIR. Consideramos primordial la planificación de acciones formativas que se traduzca en un aumento de los conocimientos y aptitudes necesarias para su correcto manejo, ya que ello se traduciría en una mayor agilidad del sistema, una mejor asistencia sanitaria y un mejor cribado de derivaciones especializadas.(AU)

Introduction: Pathology of the musculoskeletal system is a frequent cause of healthcare requirements. Knowledge of musculoskeletal medicine (MSM) should be essential for most specialties. Unfortunately, many medical intern residents (MIRs) admit to a lack of confidence and competence in this field. Material and methods: 50 recently hired MIRs (32 of whom were COT residents from the Comunidad Valenciana) completed the Freedman and Berstein test of basic competency in MSM. In addition, they completed a questionnaire about their confidence in performing five common tasks in clinical practice and their perception of the curricular importance of medicine in their academic training. Results: The overall mean score obtained on the test was 69.44% (SD 13.32%), while the specific score for 5 “red flags” questions was 14.34% (SD 2.58%). Both of them showed significant differences between COT residents and other specialties.The median obtained in the evaluation of the level of confidence in wound examination was 2 above 5 (IQR 2), with significant differences (p=.014) between the COT group and other specialties. The perception of the time spent in the faculty on MSM was considered adequate (median 3, IQR 1). 64% of participants would modify the approach to the practical part of the curriculum in MME. Conclusions: The overall test was passed by 50% of the residents, which shows that the teaching of MME is deficient during the university and pre-MIR training period. We believe that it is important to plan training actions to increase the knowledge and skills necessary for its correct handling; this way, the system would be more efficient with better health care and a better screening of specialised derivations.(AU)

Skills and knowledge in musculoskeletal medicine in medical graduates prior to their incorporation into the residency system of the National Health System / Aptitudes y conocimientos en medicina musculoesquelética en licenciados en medicina previo a su incorporación al sistema de residencia del Sistema Nacional de Salud

Introduction: Pathology of the musculoskeletal system is a frequent cause of healthcare requirements. Knowledge of musculoskeletal medicine (MSM) should be essential for most specialties. Unfortunately, many medical intern residents (MIRs) admit to a lack of confidence and competence in this field. Material and methods: 50 recently hired MIRs (32 of whom were COT residents from the Comunidad Valenciana) completed the Freedman and Berstein test of basic competency in MSM. In addition, they completed a questionnaire about their confidence in performing five common tasks in clinical practice and their perception of the curricular importance of medicine in their academic training. Results: The overall mean score obtained on the test was 69.44% (SD 13.32%), while the specific score for 5 “red flags” questions was 14.34% (SD 2.58%). Both of them showed significant differences between COT residents and other specialties.The median obtained in the evaluation of the level of confidence in wound examination was 2 above 5 (IQR 2), with significant differences (p=.014) between the COT group and other specialties. The perception of the time spent in the faculty on MSM was considered adequate (median 3, IQR 1). 64% of participants would modify the approach to the practical part of the curriculum in MME. Conclusions: The overall test was passed by 50% of the residents, which shows that the teaching of MME is deficient during the university and pre-MIR training period. We believe that it is important to plan training actions to increase the knowledge and skills necessary for its correct handling; this way, the system would be more efficient with better health care and a better screening of specialised derivations.(AU)

Introducción: La enfermedad del sistema musculoesquelético es una causa frecuente de demanda asistencial. El conocimiento en medicina musculoesquelética (MME) debe ser esencial para gran parte de las especialidades. Desafortunadamente, gran parte de los médicos internos residentes (MIR) reconocen tener falta de confianza y de competencia en este campo. Material y métodos: Cincuenta MIR recién incorporados a su plaza (32 de ellos residentes de COT de la Comunidad Valenciana) completaron el test de competencia básica en MME de Freedman y Berstein. Además, realizaron un cuestionario sobre el grado de confianza a la hora de desempeñar 5 tareas habituales en la práctica clínica y sobre la percepción de la carga curricular de MME en su formación académica. Resultados: La puntuación media global obtenida en el test fue de 69,44% (SD 13,32%), mientras que la puntuación concreta para 5 preguntas que se consideraban «banderas rojas» fue de 14,34%(SD 2,58%). Ambas mostraron diferencias significativas entre los residentes de COT y otras especialidades.La mediana obtenida en la valoración del nivel de confianza en la exploración de heridas fue de 2 sobre 5 (IQR 2), con diferencias significativas (p=0,014) entre el grupo COT y el de otras especialidades. La percepción del tiempo dedicado en la facultad en materia de MME fue considerada como adecuada (mediana 3, IQR 1). El 64% modificaría el planteamiento de la parte práctica del currículo en MME. Conclusiones: La prueba global fue superada por el 50% de los residentes, lo cual pone de manifiesto que la enseñanza en MME es deficitaria durante el periodo universitario y formativo preMIR. Consideramos primordial la planificación de acciones formativas que se traduzca en un aumento de los conocimientos y aptitudes necesarias para su correcto manejo, ya que ello se traduciría en una mayor agilidad del sistema, una mejor asistencia sanitaria y un mejor cribado de derivaciones especializadas.(AU)

A 3D method to estimate the effect of derotational osteotomies over femoral maltorsion. / Un método 3D para estimar el efecto de osteotomías desrotadoras sobre alteraciones torsionales de fémur.

INTRODUCTION AND OBJECTIVES: Accurate measurement of femoral torsion is essential to diagnosing, correct surgical decision-making, and the preoperative planning of derotational osteotomies in a subgroup of anterior knee pain patients and patellofemoral instability. Several measurement techniques have been described with great variability in the magnitude of the values. Moreover, none of them can predict the effect of rotational osteotomy on the femoral version value. The purpose of the present work is to develop a method to reliably measure femoral torsion as well as to evaluate the effects of osteotomy on the femoral version angle. MATERIAL AND METHODS: 30 patients without previous signs neither symptoms of patellofemoral pain or patellofemoral instability and with a lower limbs CT were selected. Their femoral torsion was measured using the classic Jeanmart and the Murphy's method by two independent radiologists. Independently, two orthopedic surgeons measured femoral torsion with the 3D method described in this study. The intraclass coefficient correlation and the Bland-Altman tests were used to analyze qualitatively and quantitatively the intraobserver and interobserver variability of the method regarding the Jeanmart's and Murphy's method. The confidence interval of the Normal values of the new method were defined and a lineal regression analysis between the 3D-Jeanmart's and 3D-Muphy's methods was performed. RESULTS: The mean femoral version with the 3D method was 12.74° (SD 5.96°, 95% CI: 11.67° to 13.82°). With Jeanmart's method, it was 12.84° (SD 8.60°, 95% CI: 11.28° to 14.39°) and 15.87° (SD 10.68°, 95% CI: 13.94° to 17.80°) with Murphy's method, being these differences not statistically significant. Both interobserver and intraobserver agreement of the 3D method were high. CONCLUSION: The method presented in this study allows for the reliable quantification of femoral torsion in a reproducible way. This method can be applied in several open access 3D image programs what makes its implementation in the healthcare centers possible from now on.

Fracturas periprotésicas de fémur sobre prótesis de cadera y rodilla. Análisis de una serie de 34 casos y revisión de las series españolas en los últimos 20 años / Peri-prosthetic femoral fractures of hip or knee arthroplasty. Analysis of 34 cases and a review of Spanish series in the last 20 years

Objetivo. Evaluar las fracturas periprotésicas de fémur analizando las características de los pacientes, el tipo de tratamiento y los resultados, y compararlas con las series españolas publicadas en los últimos 20 años. Material y método. Evaluación retrospectiva de las fracturas periprotésicas de fémur atendidas en nuestro centro entre 2010 y 2014. Revisión de las historias clínicas y encuesta telefónica sobre la situación actual. Resultados. Hemos analizado 34 fracturas periprotésicas de fémur, 20 sobre prótesis de cadera y 14 sobre prótesis de rodilla. La edad media fue 79,9 años. El 91% tenían comorbilidad previa y hasta un 36% tenían al menos 3 enfermedades sistémicas previas. La estancia hospitalaria media fue 8,7 días, mayor en los casos tratados quirúrgicamente. Hasta el 60,6% de los pacientes presentaron complicaciones y la tasa de mortalidad ha sido del 18%. El 61,5% de los pacientes no recuperaron el estado funcional previo a la fractura, con mayor dolor en los pacientes con artroplastia de cadera. Discusión. Las fracturas periprotésicas de fémur son cada vez más frecuentes, porque cada vez se realizan más artroplastias y en pacientes más mayores. El tratamiento es complejo, porque a la propia dificultad de la fractura se añade la presencia de un implante previo, la baja calidad ósea y la comorbilidad. Conclusiones. Las fracturas periprotésicas de fémur suponen una merma en la calidad de vida de los pacientes. Requieren un tratamiento individualizado. La tasa de complicaciones y de mortalidad es muy elevada (AU)

Purpose.To evaluate peri-prosthetic femoral fractures by analysing type of patient, treatment and outcomes, and to compare them with Spanish series published in the last 20 years. Material and methods.A retrospective review of the medical records of patients with peri-prosthetic femoral fractures treated in our hospital from 2010 to 2014, and telephone survey on the current status. Results. A total of 34 peri-prosthetic femoral fractures were analysed, 20 in hip arthroplasty and 14 in knee arthroplasty. The mean age of the patients was 79.9 years, and 91% had previous comorbidity, with up to 36% having at least 3 prior systemic diseases. Mean hospital stay was 8.7 days, and was higher in surgically-treated than in conservative-treated patients. The majority (60.6%) of patients had complications, and mortality was 18%. Functional status was not regained in 61.5% of patients, and pain was higher in hip than in knee arthroplasty. Discussion. Peri-prosthetic femoral fractures are increasing in frequency. This is due to the increasing number of arthroplasties performed and also to the increasing age of these patients. Treatment of these fractures is complex because of the presence of an arthroplasty component, low bone quality, and comorbidity of the patients. Conclusion. Peri-prosthetic femoral fractures impair quality of life. They need individualised treatment, and have frequent complications and mortality (AU)

Peri-prosthetic femoral fractures of hip or knee arthroplasty. Analysis of 34 cases and a review of Spanish series in the last 20 years. / Fracturas periprotésicas de fémur sobre prótesis de cadera y rodilla. Análisis de una serie de 34 casos y revisión de las series españolas en los últimos 20 años.

PURPOSE: To evaluate peri-prosthetic femoral fractures by analysing type of patient, treatment and outcomes, and to compare them with Spanish series published in the last 20 years. MATERIAL AND METHODS: A retrospective review of the medical records of patients with peri-prosthetic femoral fractures treated in our hospital from 2010 to 2014, and telephone survey on the current status. RESULTS: A total of 34 peri-prosthetic femoral fractures were analysed, 20 in hip arthroplasty and 14 in knee arthroplasty. The mean age of the patients was 79.9 years, and 91% had previous comorbidity, with up to 36% having at least 3 prior systemic diseases. Mean hospital stay was 8.7 days, and was higher in surgically-treated than in conservative-treated patients. The majority (60.6%) of patients had complications, and mortality was 18%. Functional status was not regained in 61.5% of patients, and pain was higher in hip than in knee arthroplasty. DISCUSSION: Peri-prosthetic femoral fractures are increasing in frequency. This is due to the increasing number of arthroplasties performed and also to the increasing age of these patients. Treatment of these fractures is complex because of the presence of an arthroplasty component, low bone quality, and comorbidity of the patients. CONCLUSION: Peri-prosthetic femoral fractures impair quality of life. They need individualised treatment, and have frequent complications and mortality.